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Finding cures. All of them.

We approach therapeutic discovery as a unified optimization problem across the entire landscape of human disease.

Image by Allison Saeng

Drug discovery is reaching its structural limits

For decades, modern drug discovery followed a familiar path: select a biological target, design a molecule around it, test it experimentally, and advance the most promising candidates. This process produced many important medicines, but it is showing clear signs of exhaustion.

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Industry-wide, the cost per approved drug has ballooned to $2.5 billion, development timelines have extended to 12–15 years, and the probability that a candidate entering clinical trials will reach approval has fallen below 7%. These trends reflect the increasing complexity of human biology and the gradual exhaustion of the most accessible therapeutic mechanisms.

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Addressing today’s unmet medical needs requires discovering new patterns, new mechanisms, and new molecular opportunities — capabilities that the traditional, hypothesis-driven model was not designed to deliver at scale.

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Our Philosophy:
Systematic Discovery

Rather than selecting a narrow set of targets and designing molecules around them, we pursue a strategy of systematic, large-scale exploration across biological space. By generating broad interaction data across protein families and diverse chemical domains, we build a high-resolution map of therapeutic opportunities that is not constrained by human intuition or historical assumptions.

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The sheer scale of biological space makes exhaustive exploration impossible. AI provides the mechanism for directing this exploration efficiently and intelligently.

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By designing the system with no human in the loop, we enable unbiased, data-driven progress at a speed and scale unattainable through traditional workflows.

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Partnerships and Collaboration

Systematic, computational exploration does not replace the detailed biological research conducted in academic laboratories, medical centers, and clinical settings. Instead, it enhances and accelerates it.

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Researchers provide deep expertise in disease mechanisms, genetic factors, patient phenotypes, and clinical context. Our platform can apply these insights at scale — testing hypotheses in days rather than months, exploring related mechanisms, and generating optimized molecular candidates for experimental validation.

6063 Imperial Loop Drive

College Station, TX 77845

© 2025, Novel Therapeutics.

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